Authors

Mohammed Al Otaiby, Adult Interventional Cardiology Department- Prince Sultan Cardiac Center- Riyadh- KSAFollow
Turki A. Al Garni, Adult Interventional Cardiology Department- Prince Sultan Cardiac Center- Riyadh- KSAFollow
Abdullah Alkhushail, Adult Interventional Cardiology Department- Prince Sultan Cardiac Center- RiyadhFollow
Abdulrahman Almoghairi, Adult Interventional Cardiology Department- Prince Sultan Cardiac Center- Riyadh- KSA
Sondos Samargandy, (1) Adult Interventional Cardiology Department- Prince Sultan Cardiac Center- Riyadh- KSA
Monirah Albabtain, Cardiology Clinical Pharmacy Department- Prince Sultan Cardiac Center- Riyadh- KSAFollow
Amr A. Arafat, Adult Cardiac Surgery Department- Prince Sultan Cardiac Center- Riyadh- KSAFollow
Hussein Alamri, Adult Interventional Cardiology Department- Prince Sultan Cardiac Center- Riyadh- KSAFollow

The Trans-Septal Approach In Transcatheter Mitral Valve-In-Valve Implantation For Degenerative Bioprosthesis

Abstract

Background: Transcatheter Mitral Valve-in-Valve Implantation (TMViVI) has recently emerged as a novel therapy for degenerated mitral valve bioprosthesis. Re-operative mitral valve surgery is associated with a substantial risk of mortality and morbidity. The objective of this study was to describe the outcomes of transcatheter mitral valve-in-valve implantations in our cardiac center.

Methods: Twenty-two patients underwent the valve-in-valve procedure because of bioprosthesis degeneration from March 2017 to October 2018. Clinical, echocardiographic, procedural details and survival at follow up were assessed.

Results: Eight patients refused re-operative cardiac surgery while others were deemed a high risk for conventional re-operative sternotomy. All patients had TMViVI performed via a trans-septal approach, and the prosthesis was implanted successfully with immediate hemodynamic improvement in 20 patients. One patient had tamponade (4.55%), two had permanent pacemaker insertion (9.09%), two patients had a renal impairment (9.09%), and three patients had vascular complications (13.64%). There was one aborted procedure for the failure to cross the tissue valve with a transcatheter valve, and one patient was converted to an emergency mitral valve surgery. All patients were discharged in NYHA class I/II and NYHA class was markedly improved at one-year follow-up (p= 0.002).

Conclusions: Trans-septal mitral valve-in-valve implantation can be performed safely for degenerative mitral valve bioprosthesis and with favorable early clinical and hemodynamic outcomes.

Recommended Citation

Al Otaiby, Mohammed; Al Garni, Turki A.; Alkhushail, Abdullah; Almoghairi, Abdulrahman; Samargandy, Sondos; Albabtain, Monirah; Arafat, Amr A.; and Alamri, Hussein (2020) "The Trans-Septal Approach In Transcatheter Mitral Valve-In-Valve Implantation For Degenerative Bioprosthesis," Journal of the Saudi Heart Association: Vol. 32 : Iss. 2 , Article 12.
Available at: https://doi.org/10.37616/2212-5043.1036

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