Abstract
Background: Incidence and outcomes of acute kidney injury (AKI) among neonates who underwent open-heart surgery are not well highlighted in the literature. We aim to assess the incidence, risk factors, and outcome of AKI among neonates undergoing open-heart surgery. Methods: This is a retrospective cohort study between 2016 and 2021 for all neonates requiring open heart surgery. The cases were divided into 2 groups: the AKI (index) group and the non-AKI (control) group. The two groups were statistically compared for risk factors, needs for dialysis, and outcomes. Results: 100 patients fulfilled the inclusion criteria. Among them, 74 (74%) developed AKI, including 41 (55%), 15 (21%), and 18 (24%) patients in KDIGO stages 1, 2, and 3, respectively. Multivariate analysis comparing both groups demonstrated that low preoperative creatinine (p =0.01), prolonged bypass time (p=0.0004) and high vasoactive inotropic score (VIS), (p=0.0008) were risk factors for developing AKI post-operatively. Furthermore, in the AKI group, 17 (23%) neonates required renal replacement therapy in the form of peritoneal dialysis. The length of stay was higher in the AKI index group (p=0.015). Patients who had AKI recovered their kidney function at discharge. There was no difference in mortality between both groups.
Recommended Citation
Alghamdi, Faisal A.; Bin Mahfooz, Mohammed A.; Almutairi, Hatim F.; Alshaiban, Nasser S.; Alotibi, Khaled E.; Kabbani, Omar M.; and Kabbani, Mohamed S.
(2024)
"Incidence, Risk Factors and Outcomes of Acute Kidney Injury in Neonates Undergoing Open-Heart Surgeries: Single Center Experience,"
Journal of the Saudi Heart Association: Vol. 36
:
Iss.
2
, Article 2.
Available at: https://doi.org/10.37616/2212-5043.1374
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